Ultrasound Fast Alternative to MRI for Breast Implant Status
Pam Harrison
April 01, 2014
LAS VEGAS — High-resolution ultrasound done in a physician's office is a fast, convenient, and friendly alternative to MRI for ascertaining the status of breast implants, a pilot study suggests.
Researchers found a "higher than expected" rotation rate in 2 types of shaped cohesive gel implants and detected 2 ruptures that were later confirmed on MRI.
Dr. William Adams Jr.
"Clinically, our rotation rate is only about 2%. It was surprising that we were definitely able to show with ultrasound that the rotation rate was much higher," said William Adams Jr., MD, clinical associate professor of plastic surgery at the University of Texas South Western Medical Center in Dallas.
"This means that a fair number of rotations are going unnoticed by patients. We haven't had this type of information about shaped implants before, so it's something we can add to our discussion with patients when they are considering these types of surgeries," he told Medscape Medical News.
The study results were presented here at the American Institute of Ultrasound in Medicine (AIUM) 2014 Annual Convention in Las Vegas, Nevada.
MRI Screening
Currently, the US Food and Drug Administration (FDA) recommends that breast implant recipients undergo MRI screening 3 years after implantation and every other year thereafter to determine whether an implant has ruptured. However, even in the best studies, there is at least a 15% false-positive rate, Dr. Adams noted.
This means that a woman might be rescheduled for breast implantation surgery only to have the surgeon discover the implant was intact.
In addition, "MRIs aren't much fun for the patient; they're loud, the patient has to lie still for a long time, and they are very expensive," said Dr. Adams.
Because of this, very few women ever go for an MRI, especially when their implants seem to be fine, he said.
In fact, rotation is not an issue with round breast implants; orientation is an issue only for implants that resemble the natural shape of the breast, where rotation could result in a misshapen breast. Rotational status cannot be determined with MRI.
The researchers evaluated 74 patients with bilateral shaped cohesive gel implants using ultrasound. Of the implants in this cohort, 48 were Allergan 410 and 100 were Mentor CPG.
Both types of implants have a textured outer shell and untextured fiducial markers on their surface at the lower pole, which allow the surgeon to feel and assess implant orientation during surgery, the researchers report. It was previously assumed that textured implants become anchored to the surrounding tissue and do not rotate.
The fiducial markers were imaged using a Terason 2000+ ultrasound system with a TouchView linear array probes.
The ultrasound examination itself is painless and nonthreatening, much like the fetal–maternal ultrasound screening many women are familiar with, Dr. Adams noted.
Marker orientation relative to the nipple was determined by using a clock-hand position, where 6 was directly downward and 3 directly to the right. Any orientation between 5 and 7 o'clock was considered to be "unrotated."
On ultrasound examination, which took place 6 months to 7 years after implantation, 25% of the Mentor CPG implants and 21% of the Allergan 410 implants had rotated from their original position.
"The vast majority of these rotations will 'self-reverse' and the implant will reorient itself over time, so it's somewhat of a dynamic process," said Dr. Adams.
"Still, my personal opinion is that ultrasound will eventually replace MRI. It just has to have FDA 'blessing' before surgeons can openly recommend it," he explained.
The percentage of women who follow the FDA recommendation and go for MRI screening is not known, said Brad Bengtson, MD, from the Bengtson Center for Aesthetics and Plastic Surgery in Grand Rapids, Michigan. However, he told Medscape Medical News that he would be "shocked" if it were over 3%.
Dr. Bengtson and his colleagues published the first landmark evaluation of high-resolution ultrasound for the detection of breast implant shell failure (Aesthet Surg J. 2012;32:157-174). They concluded that the ultrasound approach is equivalent to MRI in terms of visualization of implant rupture, but that its relative accessibility, affordability, and real-time visualization represent "significant potential advantages" over MRI for this indication.
"Since our original research began in 2012, we have imaged more than 500 patients and detected more than 80 patients with implant shell failure. And in every patient with a rupture who has gone to surgery, shell failure has been confirmed, with no false-positives to date," Dr. Bengtson reported. "Patients need a better solution than MRI to follow their breast implants over time; unquestionably, that technology is high-resolution ultrasound."
Tổng số lượt xem trang
Thứ Tư, 9 tháng 4, 2014
Chủ Nhật, 6 tháng 4, 2014
THYROID HEMANGIOMA
Discussion
Thyroid hemangiomas are extremely rare, and there are only a few cases reported in literature reviews. Most thyroid hemangiomas are not palpable and are diagnosed incidentally
during imaging examinations. A hemangioma is a benign vascular tumor of 2
common types, capillary and cavernous, based on the size of the vessels
involved. In most cases, thyroid hemangiomas are secondary to trauma or fine-needle
aspiration biopsy. Secondary hemangiomas have been described as pseudomalformations, representing vascular proliferation after organization of a thyroid hematoma.Two
case reports described exuberant vascular proliferation in the thyroid
occurring secondary to fine-needle aspiration. Organization of the hematoma
generally results in complete resolution, but it can give rise to vascular and
fibroblastic proliferative changes that resemble a cavernous hemangioma. Our patients had no history of trauma,
fine-needle aspiration, biopsy, or other invasive procedures in the neck;
therefore, we believe that our cases were primary thyroid hemangiomas. Primary
hemangiomas are extremely rare developmental anomalies resulting from the
inability of the angioblastic mesenchyme to form canals. Previous studies
reported that preoperative diagnosis of a thyroid hemangioma is difficult
because there are no specific pathognomonic findings on sonography, fine-needle
aspiration cytologic examination, or even CT. Heterogeneous signal intensity and a serpentine pattern on magnetic resonance
imaging are considered highly suggestive of cavernous hemangiomas. However,
there are a few reports of sonographic findings of hemangiomas in other
superficial organs such as the breast. These studies reported that hemangiomas
were lobulated, well-circumscribed masses, usually with heterogeneous or
complex echogenicity due to the presence of multiple vascular channels and
phleboliths. Our cases of thyroid hemangiomas showed well-circumscribed hypoechoic
lesions with internal multiple linear septations on sonography, which were very
similar to previously reported sonographic findings of hemangiomas. Another sonographic
characteristic of a superficially located hemangioma is the compressibility of
the blood-filled lesion unless it is fully thrombosed. During the sonographic examinations, our
lesions were compressible under the probe, and the lesion volume decreased
after the bloody content was aspirated on fine-needle aspiration. We think that
these lesions were vascular malformations such as hemangiomas based on the
characteristic sonographic findings and confirmation of bloody content during
fine-needle aspiration.
Innumerable internal septations on sonography may be related
to the presence of multiple small vascular channels seen pathologically in
hemangiomas, and large blood-filled spaces or sinuses have been previously
reported in cavernous hemangiomas.Our cases were pathologically confirmed to be
cavernous hemangiomas after surgery. Pathologically, cavernous hemangiomas are
typically discrete multiloculated lesions containing evidence of hemorrhage in various stages
of evolution. They lack smooth muscle and elastic fibers and are lined by a
single layer of endothelium and differing quantities of subendothelial fibrous
stroma. In most reported series, cavernous hemangiomas underwent periodic rapid
growth, but in our first case, there was no interval change on follow-up
sonography after 6 months or 1 year.
Coarse calcifications are often suggested to be a reliable
sign of hemangiomas. However, in our cases, there was no sign of calcifications
in the lesions on sonography or CT. Fine-needle aspiration cytologic
examination seems to be inconclusive in the diagnosis of hemangiomas because it
reveals only blood. Multiple fine-needle aspiration biopsies have not been
shown to be useful in obtaining sufficient cellular material. However, we think
that confirmation of bloody content by aspiration could be very helpful for
preoperative diagnosis of thyroid hemangiomas when combined with characteristic
sonographic findings. Core needle biopsy is usually contraindicated in hemangiomas
because of the high risk of bleeding, but many hemangiomas have been diagnosed
by core needle biopsies in intramuscular sites and the breast, and some authors suggest
that core needle biopsy is a safe diagnostic procedure for hemangiomas. The definite diagnosis of a thyroid hemangioma is based
on histologic findings. Complete surgical excision is usually recommended when
a hemangioma is diagnosed.
Although there is the widespread perception that preoperative
diagnosis of thyroid hemangiomas on sonography is difficult because there are
no specific pathognomonic findings, we suggest that a more careful
interpretation of sonograms with reference to characteristic imaging findings,
such as a well-circumscribed hypoechoic structure with innumerable internal septations, may lead to a precise preoperative diagnosis of a thyroid hemangioma. In addition,
although fine-needle aspiration cytologic results are usually insufficient,
confirmation of bloody content during aspiration can further support a
diagnosis of a thyroid hemangioma.
The presence of heterogeneous signal intensity and a serpentine
pattern on magnetic resonance imaging is usually considered diagnostic for
hemangiomas. Other imaging modalities such as single-photon emission CT,
digital subtraction angiography, and red blood cell scans can provide
additional information in the diagnosis of hemangiomas; however, such
examinations are often not performed routinely because of their high cost and nonavailability, as
in the cases described here.
Accurate preoperative diagnosis allows better preoperative
planning, and adequate preoperative characterization is very important because
bleeding is common in hemangiomas; in one series, intraoperative blood loss was
in excess of 2 L. A previous report emphasized the importance of ensuring that
the integrity of a thyroid hemangioma is maintained to minimize blood loss during surgery.
This report describes 2 cases of thyroid hemangiomas that
were diagnosed on sonography. These cases demonstrate that thyroid hemangiomas can
be diagnosed correctly by sonography with or without confirmation of bloody
content in the lesions by fine-needle aspiration.
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