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Thứ Sáu, 21 tháng 4, 2017

WFUMB 2017 TAIPEI: ABSTRACTS REGISTRATED from MEDIC


1. Checkered Appearance of Color Doppler in Diagnosing of Spontaneous Isolated Dissecting Aneurysm of the Superior Mesenteric Artery in Four Cases
Tai Van Le, MD, Hai Thanh Phan, MD
MEDIC Medical Center, HCM City, Vietnam

Objectives: To describe ultrasound findings and role of color Doppler in diagnosing of spontaneous isolated dissecting aneurysm of the superior mesenteric artery.
Methods: From 2015 – 2016, four cases were collected, male, age 48-60 years (mean age 53), diagnosis base on B-Mode and color Doppler which were confirmed by CT. All cases were in mild epigastric pain during scanning. There were three cases with acute onset epigastric pain sharply, relieve but not in recovery. In which the first case lasted one month, the second case lasted two months and the third case had acute epigastric pain for 2 days accompanied vomiting, dyspepsia and abdominal distension. Melena was noted in last case.
Results: The dissecting aneurysm happens at proximal part and extending to distal part, bigger than 10 mm in diameter, with intimal flap inside to split into true and false lumen. The flapping of intimal flap is not very clear.  There were two cases with false lumens contain fully thrombosis. The checkered appearance of color Doppler images represented in three cases. Two cases were endovascular stenting, conservative therapy for one, and last case unknown final result.
Conclusions: The checkered appearance of color Doppler images is typical pattern for diagnosing of dissecting aneurysm of superior mesenteric artery that can help in case of  not clear thin intimal flap.



2.  ACOUSTIC  RADIATION FORCE IMPULSE  IMAGING (ARFI)  of ULTRASOUND in ASSESSMENT  of PANCREAS DISORDERS
 Nguyen Thien Hung-Phan Thanh Hai.
MEDIC MEDICAL CENTER, HCMC, VIETNAM

ABSTRACT:
PURPOSE :
 To evaluate pancreas elastic characters  using ARFI technique in normal individuals, diabetic patients and patients in mild acute pancreatitis.
 MATERIAL and METHODS:
Using SIEMENS S2000 with VTI and VTQ techniques to evaluate pancreatic tissue [head, body and tail with 3 times measurements  for  each part of pancreas] . There were total of  30 normal individuals  (age 20-40), and 34 diabetic patients suffering  from  diabetes  for 2-10 years enrolled in this study.  Patients were fasting 8 hours before ultrasound examination and in half sitting position. Statistic and data were treated by MedCalc software.
 RESULTS and DISCUSSIONS:
Elastic mean velocity ARFI of normal pancreas from normal individuals was V1= 0.96+/-0.16 m/s (range 0.6-1.19m/s), and more faster [harder] in diabetic patients, V1= 1.32+/-0.18 m/s.  There was significant statistic difference of elastic velocity in 2 groups (p under 0.0001). In diabetic patients, diabetic tissue  is getting fibrosis for a determined time [2 years, 5 years  and 10 years] , while cystic masses  and acute pancreatitis  getting harder . ARFI techniques reveals pancreatic tissue harder in old patients and  suffering from diabetes  for years.
 CONCLUSION:
Using ARFI techniques in routine daily clinical activities could help evaluating elastic properties of pancreas in diabetes and pancreatic disorders. 
REFERENCES:
1/ Virtual analysis of pancreatic cystic lesion fluid content by ultrasound  ARFI Quantification, JUM
2013.
2/ Use ARFI Elastography to Diagnose Acute Pancreatitis at Hospital Admission, JUM 2014. 

Point of care ultrasound: A new tool for the 21st century nephrologist

Point of care ultrasound: A new tool for the 21st century nephrologist



Abstract
There is an exciting change happening in nephrology training. Across the country, nephrology programs are bringing point of care ultrasound into their curricula. Nephrologists and nephrology trainees are not only using point of care ultrasound for the assessment of kidneys and bladder but also for volume assessment. In this article, we describe how our nephrology division designed a hands-on point of care ultrasound course for nephrology fellows. We also describe some important anecdotes from our experience that highlight the utility of this novel tool.
A new assessment tool for nephrologists
Across the country, nephrology fellows are being taught to use ultrasound at the point of care to make timely decisions about their patients.1 ,2 The movement to incorporate ultrasound training into nephrology dates back about a decade. In 2008, a survey of nephrology program directors found that some programs already offered training in diagnostic renal ultrasound and that 13% of programs planned to formally incorporate performance and interpretation of ultrasound into their curricula within a year.3 In a follow up survey in 2014, we found that most programs still did not have ultrasound training but that some programs offered two- or four-week rotations.4
Neither survey differentiated between ultrasound performed as a formal study and those performed at the bedside. In the last few years, ultrasound machines have become more portable and more affordable. Availability is increased as many emergency departments and ICUs house their own ultrasound machines. Therefore, opportunity exists for nephrologists to use ultrasound at the point of care to determine kidney size, measure bladder volume, assess for hydronephrosis, and even to evaluate volume status. Thus, the future of ultrasound training in nephrology may be in teaching-focused exams to answer discrete clinical questions rather than teaching complete examinations of the retroperitoneum and bladder.
At our institution, we are privileged to have international experts in point of care ultrasound in our critical care faculty. They have been instrumental in popularizing and promoting a whole-body approach to point of care ultrasound (POCUS). Each year they give several three-day courses for the American College of Chest Physicians as well as a course for incoming pulmonary and critical care fellows. They have done a substantial amount of educational research and have refined their technique over time.5 In the last decade, this teaching faculty at Hofstra-Northwell School of Medicine have instructed more than 15,000 trainees and have organized a focused course for our nephrology division.6
A significant portion of the course focused on using lung ultrasound to assess volume status. Lung ultrasound has the potential to be a revolutionary, paradigm-shifting tool for leading-edge nephrologists (see sidebar).


How a lung ultrasound can help measure volume
Over the last two decades, intensivist Daniel Lichtenstein has demonstrated that when an ultrasound beam hits the surface of a normal lung, it generates artifacts called an “A line.” When an ultrasound beam hits a lung filled with water, it generates a reverberation artifact that juts away like a bright white rocket. These lung rockets are called “B lines.”7  A lines and B lines are shown in Figure 1. Research has shown that B Lines correlate with gold standards of volume assessment.


Figure 1. A lines (left image) are horizontal artifacts that appear parallel to the pleural line and indicate a normally aerated lung. B lines (right image) are reverberation artifacts generated by water-thickened interlobular septa and represent pulmonary edema in the appropriate clinic setting.
For nephrologists who are unfamiliar with lung ultrasound, there are three “need to know” points. First, B lines are a reliable method for determining volume status in dialysis patients. Second, a higher number of B lines in these patients correlates with greater mortality. Third, lung ultrasound is teachable and takes less than ten minutes to perform.
Since our initial training course in 2015 and subsequent refresher course in 2016, our division has started to incorporate point of care ultrasound into clinical practice. In one illustrative example, we were faced with an elderly woman with chronic kidney disease who was admitted with an acute exacerbation of congestive heart failure. In the setting of diuresis, the patient’s creatinine rose and she developed acute kidney injury. Her volume status became difficult to discern by traditional physical examination and we were concerned that we had gone too far with the diuretics. Emboldened by our newly acquired skills, we performed a lung ultrasound. We found that the patient had a diffuse B line pattern consistent with pulmonary edema––not seen on chest x ray or appreciated on lung auscultation. Diuretics were increased and the patient’s creatinine improved back to baseline as her heart failure resolved.
In another example, we used focused renal ultrasound to assess an elevated creatinine in a patient being considered for a left ventricular assist device (LVAD). In these patients, it is of paramount importance to identify whether the patient’s kidneys are intrinsically normal. At the time we evaluated this patient we did a point of care ultrasound examination. The kidneys were normal in size and had normal cortical thickness, there was no hydronephrosis, and the patient’s bladder was collapsed around the indwelling urethral catheter. This timely information, in conjunction with a bland urine sediment and a low urine sodium, enabled us to confidently identify the patient’s heart failure as the cause of his kidney injury. Ultimately the patient’s creatinine returned to normal two days after LVAD placement.
The value of being able to rapidly discover urinary obstruction is immeasurable. A patient presented to our outpatient clinic for evaluation of an elevated creatinine. Based upon history, obstruction was suspected. A quick look at the patient’s bladder post void proved the case. The patient was referred to a same day urology appointment where an indwelling urethral catheter was placed. In this case, hospitalization was averted and a brewing renal injury was recognized early.