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Thứ Bảy, 30 tháng 6, 2018

US first for Assessing Acute Appendicitis

By AuntMinnie.com staff writers
June 22, 2018 -- Ultrasound, CT, and MRI are all viable supplemental imaging modalities for assessing acute appendicitis after initial ultrasound, according to a study published online June 19 in Radiology.

The team led by Dr. Kevin Eng conducted a literature search on Medline and Embase, identifying studies that used surgery or histopathologic exam information alone or in combination with clinical follow-up or chart review to assess the diagnostic accuracy of supplemental imaging modalities for appendicitis.
Studies included the following:
  • For children -- ultrasound: six studies and 548 patients; CT: nine studies and 1,498 patients; MRI: five studies and 287 patients
  • For adults -- ultrasound: three studies and 169 patients; CT: 11 studies and 1,027 patients; MRI: six studies and 427 patients
All three modalities had comparable, high accuracy for diagnosing the disease, both in children and adults, the researchers found.
Pooled sensitivities and specificities of second-line imaging for diagnosing appendicitis
Sensitivity: Adults83.1%89.9%97.4%
Sensitivity: Children91.3%96.2%89.9%
Specificity: Adults90.9%93.6%97.1%
Specificity: Children95.2%94.6%93.6%
"All three modalities may be valid as second-line imaging in a clinical imaging pathway for diagnosis and management of appendicitis," they concluded.

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